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Tedizolid. Tedizolid is an oxazolidinone antibiotic with a spectrum of activity similar to that of linezolid, although it may have activity against some linezolid -resistant gram-positive cocci. In clinical trials, risk of serotonin syndrome and thrombocytopenia was lower with tedizolid than with linezolid.
Tedizolid. Tedizolid là một chất kháng sinh oxazolidinone với một phổ kháng khuẩn như linezolid, mặc dù nó có hoạt tính chống lại một số cầu khuẩn gram dương kháng linezolid. Trong các thử nghiệm lâm sàng, nguy cơ hội chứng serotonin và giảm tiểu cầu với tedizolid thấp hơn so với ...
The effects of tedizolid phosphate on fertility in humans have not been studied. Animal studies with tedizolid phosphate do not indicate harmful effects with respect to fertility (see section 5.3). 4.7 Effects on ability to drive and use machines Sivextro may have a minor influence on the ability to drive and use machines as it may cause
7 de feb. de 2022 · Tedizolid is an oxazolidinone antibiotic with high potency against Gram-positive bacteria and currently prescribed in bacterial skin and skin-structure infections. The aim of the review was to summarize and critically review the key pharmacokinetic and pharmacodynamic aspects of tedizolid. Tedizolid displays linear pharmacokinetics with good ...
La unión del tedizolid a las proteínas plasmáticas humanas es de aproximadamente el 70 al 90%. El volumen medio de distribución en estado estacionariode tedizolid en adultos sanos después de una dosis intravenosa única de tedizolid fosfato 200 mg osciló 67-80 L (aproximadamente el doble de agua corporal total).
6 de ene. de 2021 · Abstract. The most relevant information on the clinical uses of tedizolid from studies published in the last 18 months is presented in this brief review. The most important data indicate better tolerance and safety profile of long-term therapeutic regimes in off-label indications, such as osteoarticular infections and those caused by mycobacteria.
Las oxazolidinonas son una clase de antibióticos que se usan para tratar infecciones graves, a menudo después de que otros antibióticos hayan sido ineficaces. Las oxazolidinonas comprenden los fármacos siguientes: Las oxazolidinonas impiden que las bacterias produzcan las proteínas que necesitan para crecer y multiplicarse.
