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  1. 22 de may. de 2024 · Targeted radionuclide therapy, in which radiopharmaceuticals deliver potent radionuclides to tumours for localized irradiation, has addressed unmet clinical needs and improved outcomes for ...

  2. 21 de may. de 2024 · The development of NGP-42 represents a promising advancement in targeted cancer therapy, offering both specific recognition of tumor cell surface receptors and selective degradation of oncogenic proteins within those cells.

  3. 13 de may. de 2024 · Targeted therapy has been developed to meet that challenge, showing a substantially increased therapeutic index compared with conventional cancer therapies.

  4. Hace 6 días · Immunotherapy and targeted medications are two relatively new cancer treatment options that work by enhancing your immune response or interrupting a specific process on the timeline of...

  5. 28 de may. de 2024 · Starting with methotrexate and 5-fluorouracil, advancing through tyrosin kinase inhibitors (TKI) and hormone therapy, current targeted therapy is oriented toward the use of multi-targeting drugs. In general terms, an oncologic therapy can be considered targeted when a drug blocks tumor-specific metabolic pathways.

  6. Hace 2 días · Radionuclide-conjugated drugs are a category of therapeutic agents that merge radionuclides with distinct drug molecules. The fundamental concept underlying nuclide-conjugated drugs is to guide radionuclides to specific treatment sites, where radiation is emitted through radioactive decay, inducing a lethal impact on targeted cells.

  7. 13 de may. de 2024 · Based on a wealth of research evidence, the development of drugs targeting MDM2 has received increasing attention, and multiple targeted drugs have been developed, some of which have already advanced to clinical trials. This makes targeting MDM2 a promising direction for cancer treatment.