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  1. Hace 11 horas · Maria Teresa de Filippis, a pioneer in motorsport, defied odds and broke barriers in a predominantly male domain. Born into nobility on November 11, 1926, in Marigliano, Italy, Maria was raised in a cultured environment. Despite societal expectations, her love for sports, particularly horse riding and tennis, flourished from an early age.

  2. Hace 11 horas · Frederick's longtime rival Maria Theresa, who was Joseph's mother and his co-ruler, did not want a new war with Prussia, and secretly sent messengers to Frederick to discuss peace negotiations. Finally, Catherine II of Russia threatened to enter the war on Frederick's side if peace was not negotiated, and Joseph reluctantly dropped his claim to Bavaria. [174]

  3. Hace 11 horas · BCG is a 100 year old vaccine that while preventing disseminated TB in children has limited effects on adult pulmonary disease. Interestingly, in addition to inducing adaptive immunity against Mycobacterium tuberculosis, BCG vaccination has been demonstrated to display non-specific off target effects on tumor growth and is thought to reduce all-cause pediatric infections by promoting ...