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  1. Hace 15 horas · The 5-HT 1A receptor is the most widespread of all the 5-HT receptors. In the central nervous system, 5-HT 1A receptors exist in the cerebral cortex, hippocampus, septum, amygdala, and raphe nucleus in high densities, while low amounts also exist in the basal ganglia and thalamus. [7] [8] [9] The 5-HT 1A receptors in the raphe nucleus are ...