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  1. Sir Augustus Frederick d'Este, KCH (13 January 1794 – 28 December 1848) was a relative of the British royal family and the earliest recorded person for whom a definite diagnosis of multiple sclerosis can be made.

  2. Augustus d'Este fue la primera persona en ser diagnóstica con esclerosis múltiple. Sus síntomas comenzaron a los 28 años de edad con una repentina pérdida transitoria de la vista tras el funeral de un amigo.

  3. Sir Augustus Frederick D’Esté (1794–1848) was an illegitimate royal child, a bachelor, an active member of the Aborigines Protection Society, and the earliest known person diagnosed with multiple sclerosis.

  4. 17 de oct. de 2009 · The personal diary of Sir Augustus d’Esté, born 1794 grandson of King George III of England, reveals a medical history strongly suggesting that Augustus suffered from multiple sclerosis (MS). It could well be the first record of a person having this disease.

    • Anne Marie Landtblom, Patrik Fazio, Sten Fredrikson, Enrico Granieri
    • 2010
  5. Sir Augustus Frederick d'Este (1794–1848) escribió su diario desde 1822 a 1846 relatando sus síntomas neurológicos recurrentes y discapacitantes asociados a una enfermedad que aún no sabía que se llamaría Esclerosis Múltiple.

  6. Augustus d'Este. Sir Augustus Frederick d'Este, KCH (1794-1848) was the son of Prince Augustus Frederick, Duke of Sussex and Lady Augusta Murray and the grandson of George III. His parents marriage was in contravention of the Royal Marriages Act 1772, which meant that Augustus d'Este was legally considered illegitimate .

  7. It is a singular fact that the earliest account of the symptoms and clinical history of multiple sclerosis was written by Sir Augustus d'Este, a grandson of King George III of England, who kept a personal diary and record of his disease between 1822 and 1848.