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  1. Augustus d'Este. Sir Augustus Frederick d'Este, KCH (13 January 1794 – 28 December 1848) was a relative of the British royal family and the earliest recorded person for whom a definite diagnosis of multiple sclerosis can be made. He was the only son of Prince Augustus Frederick, Duke of Sussex and his wife Lady Augusta Murray. He was a ...

  2. Sir Augustus Frederick D’Esté (1794–1848) was an illegitimate royal child, a bachelor, an active member of the Aborigines Protection Society, and the earliest known person diagnosed with multiple sclerosis. For 24 years D’Esté kept a diary, currently held in the Royal College of Physicians’ archives, which documents what he called ...

  3. 17 de oct. de 2009 · Notes In English the accent on the last letter é, Esté, allows a correct pronunciation of the Italian surname in English. References Granieri E (2006) La malattia di Augusto d’Este. A un discendente degli Estensi si deve la prima testimonianza sulla sclerosi multipla. Ferrara Voci di una Città 25:3539 Google Scholar Firth D (1941) The case of Augustus d’Estè (1794–1848): the first ...

    • Anne Marie Landtblom, Patrik Fazio, Sten Fredrikson, Enrico Granieri
    • 2010
  4. Augusto d'Este. Nació el 13 de enero de 1794 en Londres, Inglaterra. Hijo del príncipe Augusto Federico, Duque de Sussex, y de Lady August...

    • Córdoba, Córdoba, Argentina
  5. The personal diary of Sir Augustus d’Este ́, born 1794 grandson of King George III of England, reveals a medical history strongly suggesting that Augustus suffered from multiple sclerosis (MS ...

  6. We owe the first documentation of multiple sclerosis (MS) to a descendent of the Estense family. Augustus d’Este. ´ was born in 1794, grandson to the. Hannoverian King George III of England ...

  7. In a short time, the disease took on a slow progressive course with relapses and remissions, characterised by new acute symptoms which eventually led to the loss of the use of his arms. Finally, in December 1848, Augustus d'Este died at the age of 54 years, unmarried and without heirs, having suffered for 26 years from an initially intermittent ...