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What are Neuromuscular blocking agents? Neuromuscular blocking agents are potent muscle relaxants typically only used during surgery to prevent muscle movement. They are structurally related to acetylcholine (the main neurotransmitter in the body) and they cause muscle relaxation by binding to acetylcholine receptors postsynaptically (which ...
Neuromuscular-blocking drugs, or Neuromuscular blocking agents (NMBAs), block transmission at the neuromuscular junction, causing paralysis of the affected skeletal muscles. This is accomplished via their action on the post-synaptic acetylcholine (Nm) receptors.
28 de nov. de 2022 · The administration of neuromuscular blocking agents is most effective via an intravenous or intramuscular route. NMBAs are poorly absorbed if administered orally. The route of administration is dependent on the patient’s clinical condition, desired speed of action, and duration of clinical effect.
- Adebayo Adeyinka, David A. Layer
- 2022/11/28
- 2019
5 de abr. de 2022 · What are neuromuscular blocking agents used for? Neuromuscular blockade induction. Neuromuscular blockade maintenance. Rapid sequence intubation. Types of neuromuscular blocking agents Depolarizing NMBAs. Succinylcholine is the only depolarizing agent used in clinical practice. Brand names include Quelicin and Anectine.
13 de nov. de 2023 · Neuromuscular blocking agents (NMBAs) come in two forms: depolarizing neuromuscular blocking agents (eg, succinylcholine) and nondepolarizing neuromuscular blocking agents (eg, rocuronium, vecuronium, atracurium, cisatracurium, mivacurium).
- Danielle Cook, David J. Simons
- 2023/11/13
- UPMC Pinnacle, UPMC Lititz
Description. Drugs that interrupt transmission of nerve impulses at the skeletal neuromuscular junction. They can be of two types, competitive, stabilizing blockers (NEUROMUSCULAR NONDEPOLARIZING AGENTS) or noncompetitive, depolarizing agents (NEUROMUSCULAR DEPOLARIZING AGENTS).
1 de feb. de 2004 · Neuromuscular blocking drugs (NMBDs) act at several sites at the neuromuscular junction, but their main effects are as agonists and antagonists at postjunctional nicotinic receptors. Succinylcholine is the only available depolarizing NMBD; it has several undesirable side-effects.
