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Tablets: 50mg white to off-white, film-coated, capsule-shaped and engraved with “795” on one side, plain on the other. Riluzole tablets is contraindicated in patients with a history of severe hypersensitivity reactions to riluzole or to any of its components (anaphylaxis has occurred) [see Adverse ... 5.1 Hepatic Injury - Cases of drug ...
10 de feb. de 2020 · Drug Interactions. Allopurinol: May enhance the adverse/toxic effect of Riluzole. Specifically, the risk of hepatotoxicity may be increased. Management: Consider alternatives to allopurinol in patients receiving treatment with riluzole due to the potential for additive hepatotoxicity.
7 de ago. de 2019 · At the beginning of these studies, the pharmaceutical interest in this class of chemical compounds was limited, as long as the pharmacological profile of riluzole was not clearly described. Riluzole (1,6-(trifluoromethoxy)-2-benzothiazolamine, PK 26124, RP 54274, Rilutek) was found to interfere with glutamate neurotransmission in biochemical, electrophysiological, and behavioral experiments.
Riluzole is recommended for the treatment of amyotrophic lateral sclerosis, except for patients with progressive muscular atrophy, primary lateral sclerosis, or hereditary spastic paraplegia, and should be initiated promptly following disease diagnosis. A patient with lived experience of riluzole treatment for amyotrophic lateral sclerosis was ...
23 de ago. de 2023 · difficult breathing. increased thirst. nausea. pale skin. swelling of the face, fingers, or lower legs. ulcers, sores, or white spots in the mouth. unusual bleeding or bruising. weight gain. Get emergency help immediately if any of the following symptoms of overdose occur while taking riluzole:
Rilutek is indicated to extend life or the time to mechanical ventilation for patients with amyotrophic lateral sclerosis (ALS). Clinical trials have demonstrated that Rilutek extends survival for patients with ALS. Survival was defined as patients who were alive, not intubated for mechanical ventilation and tracheotomy-free.
21 de ene. de 2024 · Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight. Lung problems have happened with riluzole suspension. Call your doctor right away if you have lung or breathing problems like trouble breathing, shortness of breath, or a cough that is new or worse.
