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  1. TLDR. A previously unrecognized case of MS from 1757, long antedating Ollivier and D’Este is presented, noteworthy for the fact that it was associated with a controversial therapeutic trial, presaging the next 21=2 centuries of MS therapeutics. Expand.

  2. Augustus d'Este. Sir Augustus Frederick d'Este, KCH (1794-1848) was the son of Prince Augustus Frederick, Duke of Sussex and Lady Augusta Murray and the grandson of George III. His parents marriage was in contravention of the Royal Marriages Act 1772, which meant that Augustus d'Este was legally considered illegitimate .

  3. Media in category "Augustus d'Este". The following 5 files are in this category, out of 5 total. Augustus d'Este young.jpg 750 × 750; 78 KB. D. Firth, The case of Augustus D'Este. Wellcome L0029870.jpg 1,208 × 1,744; 1.01 MB. Detail from Augustus d'Este young (cropped).jpg 180 × 270; 10 KB.

  4. Finally, in December 1848, Augustus d'Este died at the age of 54 years, unmarried and without heirs, having suffered for 26 years from an initially intermittent disease with clinical relapses and remission of the symptoms, but with a gradual neurological deterioration. The disease had not, of course, been identified at that time.

  5. Augusto D'este está en Facebook. Únete a Facebook para conectar con Augusto D'este y otras personas que tal vez conozcas. Facebook da a la gente el poder de compartir y hacer del mundo un lugar más...

  6. We owe the first documentation of multiple sclerosis (MS) to a descendent of the Estense family. Augustus d’Este. ´ was born in 1794, grandson to the. Hannoverian King George III of England ...

  7. Augusto D. Este está en Facebook. Únete a Facebook para conectar con Augusto D. Este y otras personas que tal vez conozcas. Facebook da a la gente el poder de compartir y hacer del mundo un lugar más...