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29 de may. de 2024 · Associations between HLA types and ICI-T, ICI-DM, and ICI-HP were tested in patients of European ancestry after adjustment for type of immunotherapy (PD-1/PD-L1 monotherapy, anti-CTLA-4 monotherapy, and combination), cancer type, sex, age and 5 principal components, at each center.
13 de may. de 2024 · To investigate the associations between HLA alleles affecting antibody response and the risk of breakthrough infection and severe COVID-19 in real-world settings, we conducted a survival...
13 de may. de 2024 · In addition, through HLA typing 1,702 individuals from 11 populations of African ancestry derived predominantly from the 1000 Genomes Project, we constructed an imputation resource, fine-mapping...
14 de may. de 2024 · HLA Associations, Somatic Loss of HLA Expression, and Clinical Outcomes in Immune Aplastic Anemia. In immune aplastic anemia, HLA-B*14 and HLA class I allele loss are linked to high-risk clonal evolution after IST; more studies are needed.
Hace 4 días · Moreover, the HLA-B*15:02 and HLA-B*38:02 genotypes were significantly associated with SMX/CTX-induced SJS/TEN, while the HLA-A*68:01 and HLA-B*39:01 genotypes were associated with SMX/CTX-induced DRESS. The HLA-B*13:01 allele showed an association with SMX-CTX-induced SJS/TEN and DRESS," concluded the authors.
15 de may. de 2024 · Nomenclature for Factors of the HLA System WHO Committee . The WHO Nomenclature Committee for Factors of the HLA System comprises the following individuals: Steven G. E. Marsh (Chair) Walter F. Bodmer; Mary N. Carrington; Henry A. Erlich; Marcelo Fernández-Vina; Sebastiaan Heidt; Rhonda Holdsworth; Wolfgang R. Mayr; Martin Maiers ...
15 de may. de 2024 · We detected significant HLA associations with NB. In particular, HLA-DQB1*05:02 (OR = 1.61; p adj = 5.4 × 10 −3 ) and HLA-DRB1*16:01 (OR = 1.60; p adj = 2.3 × 10 −2 ) alleles were associated to higher risk of developing NB.
