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22 de may. de 2024 · Reverse transcriptase, an enzyme involved in the replication of several kinds of RNA virus. Reverse transcriptase synthesize DNA using RNA as template. It carries three enzymatic activities: (1) RNA dependent DNA synthesis; (2) DNA dependent DNA synthesis and (3) RNAse H activity.
14 de may. de 2024 · QPCR revealed that the mRNA levels of telomerase reverse transcriptase (Tert) and telomerase RNA ... (300 ng) was digested with 1 μl restriction enzyme RsaI, 1 μl HinfI in 2.5 μl ...
8 de may. de 2024 · Previous research has focused on inhibition of the L1 reverse transcriptase due to the prevalence of well-characterized inhibitors of related viral enzymes. Here we present the L1 endonuclease...
25 de may. de 2024 · Telomerase Reverse Transcriptase (TERT) encodes the telomerase reverse transcriptase enzyme and is the most frequently mutated gene in patients with telomeropathies. Heterozygous variants impair telomerase activity by haploinsufficiency and pathogenic variants are associated with bone marrow failure syndrome and predisposition to acute myeloid leukaemia. Owing to their rarity, telomeropathies ...
23 de may. de 2024 · Definition. cDNA (short for copy DNA; also called complementary DNA) is synthetic DNA that has been transcribed from a specific mRNA through a reaction using the enzyme reverse transcriptase. While DNA is composed of both coding and non-coding sequences, cDNA contains only coding sequences.
23 de may. de 2024 · The objective of this study is to investigate the role of telomerase reverse transcriptase (TERT) in regulating the tolerogenic feature of DCs. Methods. The telomerase was assessed in DCs, which were collected from patients with allergic rhinitis (AR), healthy control (HC) subjects, and mice.
Hace 4 días · One component is the prime editor, which combines a SpCas9 protein, used in the first CRISPR-Cas gene editing technology, and a reverse transcriptase, an enzyme that transcribes RNA into DNA.
