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  1. Margaret Holles, Duchess of Newcastle-upon-Tyne (née Cavendish; 22 October 1661 – 24 December 1715/16, London) was an English noblewoman. Margaret was born the third daughter and fourth of six children of Henry Cavendish, 2nd Duke of Newcastle-upon-Tyne and his wife, Frances Pierrepoint.

  2. The Cavendish inheritance descended in the seventeenth and eighteenth centuries through the female line, passing first from Henry Cavendish, 2nd Duke of Newcastle upon Tyne (1630-1691) to his daughter, Margaret (1661-1716) who married John Holles, 4th Earl of Clare (1662-1711).

  3. Margaret "Duchess of Newcastle" Holles formerly Cavendish. Born 22 Oct 1661 [location unknown] Ancestors. Daughter of Henry Cavendish KG and Frances (Pierrepont) Cavendish. Sister of Elizabeth (Cavendish) Montagu, Frances Cavendish, Henry Cavendish, Catherine (Cavendish) Tufton and Arabella (Cavendish) Spencer.

  4. John Holles, 3rd Duke of Newcastle upon Tyne (1662-1711), (1st Duke of 2nd creation) Thomas Pelham-Holles, 4th Duke of Newcastle upon Tyne (1693-1768), (1st Duke of 3rd creation) and 1st Duke of Newcastle under Lyne (or Line) Dukes of Newcastle under Lyne (Line), later known as Lyme.

  5. Margaret Holles, Duchess of Newcastle-upon-Tyne was an English noblewoman.

  6. Margaret Cavendish, Duchess of Newcastle-upon-Tyne (née Lucas; 1623 – 16 December 1673) was a prolific English philosopher, poet, scientist, fiction writer and playwright. In her lifetime she produced more than 12 original literary works, many of which became well known due to her high social status.

  7. The Cavendish inheritance descended in the seventeenth and eighteenth centuries through the female line, passing first from Henry Cavendish, 2nd Duke of Newcastle upon Tyne (1630-1691) to his daughter, Margaret (1661-1716) who married John Holles, 4th Earl of Clare (1662-1711).