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  1. Charles, Duke of Guise. Charles de Lorraine, 4th Duke of Guise and 3rd Prince of Joinville (20 August 1571 – 30 September 1640), was the son of Henry I, Duke of Guise and Catherine of Cleves, and succeeded his father as Duke of Guise in 1588.

  2. Count of Guise and Duke of Guise (pronounced GHEEZ) were titles in the French nobility. Originally a seigneurie, in 1417 Guise was erected into a county for René, a younger son of Louis II of Anjou.

  3. Francis I of Lorraine, 2nd Duke of Guise, 1st Prince of Joinville, and 1st Duke of Aumale (French: François de Lorraine; 17 February 1519 – 24 February 1563), was a French general and statesman.

  4. house of Guise, Noble French Roman Catholic family that played a major role in French politics during the Reformation. Claude de Lorraine (1496–1550) was created the 1st duke de Guise in 1527 for his service to Francis I in the defense of France.

    • The Editors of Encyclopaedia Britannica
  5. Charles de Lorraine, 4th Duke of Guise and 3rd Prince of Joinville (20 August 1571 – 30 September 1640), was the son of Henry I, Duke of Guise and Catherine of Cleves, and succeeded his father as Duke of Guise in 1588.

  6. Charles de Lorraine, 4e duke de Guise was the 4th duke de Guise who lived through the rapid decline in the family’s power. On the day of the assassination of his father, Henri, the 3rd duke (Dec. 23, 1588), Charles was arrested and transferred to the Château of Tours, in which he was imprisoned for.

  7. The Catholic League, now headed by the surviving Guise brother, Charles, duke of Mayenne (1554 – 1611), was weakened after initial success by war weariness and polarization between radical and moderate factions.