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  1. Sir Augustus Frederick d'Este, KCH (13 January 1794 – 28 December 1848) was a relative of the British royal family and the earliest recorded person for whom a definite diagnosis of multiple sclerosis can be made.

  2. Augustus d'Este fue la primera persona en ser diagnóstica con esclerosis múltiple. Sus síntomas comenzaron a los 28 años de edad con una repentina pérdida transitoria de la vista tras el funeral de un amigo.

  3. Sir Augustus Frederick D’Esté (1794–1848) was an illegitimate royal child, a bachelor, an active member of the Aborigines Protection Society, and the earliest known person diagnosed with multiple sclerosis.

  4. Sir Augustus Frederick d'Este (1794–1848) escribió su diario desde 1822 a 1846 relatando sus síntomas neurológicos recurrentes y discapacitantes asociados a una enfermedad que aún no sabía que se llamaría Esclerosis Múltiple.

  5. 17 de oct. de 2009 · The personal diary of Sir Augustus d’Esté, born 1794 grandson of King George III of England, reveals a medical history strongly suggesting that Augustus suffered from multiple sclerosis (MS). It could well be the first record of a person having this disease.

    • Anne Marie Landtblom, Patrik Fazio, Sten Fredrikson, Enrico Granieri
    • 2010
  6. The first case history of multiple sclerosis: Augustus d’Esté (1794–1848) AbstractThe personal diary of Sir Augustus d’Esté, born 1794 grandson of King George III of England, reveals a medical history strongly suggesting that Augustus suffered from multiple sclerosis (MS).….

  7. It is a singular fact that the earliest account of the symptoms and clinical history of multiple sclerosis was written by Sir Augustus d'Este, a grandson of King George III of England, who kept a personal diary and record of his disease between 1822 and 1848.