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Nerve growth factor (NGF) is the firstly discovered and best characterized neurotrophic factor, known to play a critical protective role in the development and survival of sympathetic, sensory and forebrain cholinergic neurons.
- Luigi Aloe, Maria Luisa Rocco, Bijorn Omar Balzamino, Alessandra Micera
- 10.2174/1570159X13666150403231920
- 2015
- 2015/05
Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival of certain target neurons. It is perhaps the prototypical growth factor, in that it was one of the first to be described.
El factor de crecimiento nervioso (NGF Nerve Growth Factor en inglés) es una proteína presente en el sistema nervioso y otros sistemas del cuerpo humano, necesaria para la supervivencia y desarrollo de las neuronas en el período embrionario.
Nerve growth factor (NGF) is an insulin-like protein, which regulates growth, development and maintenance of sympathetic and embryonic sensory neurons. It is found in varying amounts in the venom of all tested poisonous snakes and in the male mouse submaxillary gland.
Since its discovery, nerve growth factor (NGF) has long occupied a critical role in developmental and adult neuro-biology for its many important regulatory functions on the survival, growth and differentiation of nerve cells in the peripheral and central nervous system.
- Maria Luisa Rocco, Marzia Soligo, Luigi Manni, Luigi Aloe
- 10.2174/1570159X16666180412092859
- 2018
- 2018/12
21 de jul. de 2016 · Recent progress in the Nerve Growth Factor (NGF) research has shown that this factor acts not only outside its classical domain of the peripheral and central nervous system, but also on non-neuronal and cancer cells.
20 de nov. de 2020 · Nerve growth factor (NGF) is an important neurotrophin that activates nociceptive neurons to transmit pain signals from the peripheral to the central nervous system. Treatment with anti-NGF...
