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Nerve growth factor (NGF) was discovered in murine submandibular glands as a factor stimulating the growth of sensory and sympathetic ganglia 1. Low-affinity pan-neurotropic receptor (P75), specific high-affinity receptor tyrosine kinases, gp140 trkA for NGF, gp145 trkB for brain-derived neurotrophic factor (BDNF), and gp145 trkC for neurotropin 3 are known.
β-NGF, Beta-Nerve Growth Factor, is important for the development and maintenance of the sympathetic and sensory nervous systems. The active form of human β-NGF is a noncovalently disulfide-linked homodimer, and three disulfide bonds are required for biological activity. Stem Cell Factor
The NGF gene provides instructions for making a protein called nerve growth factor beta (NGFβ). This protein is important in the development and survival of nerve cells (neurons), especially those that transmit pain, temperature, and touch sensations (sensory neurons). The NGFβ protein functions by attaching (binding) to its receptors, which ...
2 de may. de 2017 · Nerve growth factor (NGF) is the first identified member of a family of neurotrophic molecules that also comprises the brain derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), NT-4, and NT-6.
神経成長因子 （しんけいせいちょういんし、 英: nerve growth factor 、略称: NGF ）は、特定の標的 神経細胞 の成長、維持、増殖、生存の調節に関与する 神経栄養因子 （ 神経ペプチド （ 英語版 ） ）である。. NGFは 成長因子 の中で最初期に記載されたものの1 ...
Nerve growth factor. Il fattore di crescita nervoso ( FCN ), o in inglese nerve growth factor ( NGF ), è una piccola proteina coinvolta nello sviluppo del sistema nervoso nei vertebrati, ed è composta da due unità di 118 aminoacidi .
Der Nervenwachstumsfaktor ( englisch nerve growth factor, Beta-NGF) ist ein Protein in Wirbeltieren. Er wurde in den 1950ern von Rita Levi-Montalcini und Viktor Hamburger entdeckt und ist einer von vielen neurotrophen Faktoren. NGF gehört zur Gruppe der Neurotrophine. Mutationen im NGF - Gen können zu einer erblichen Neuropathie (HSAN5) führen.
