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  1. Stroke has the largest contribution to the global burden and mortality (67% of all deaths) of neurological disorders. 1 Stroke is also the most common cause of acquired epilepsy in elderly individuals with an estimated incidence of 800 000 vascular epilepsy cases per year worldwide. 1,2 It remains controversial whether seizures contribute to mortality after stroke. 3-6

  2. Substances. Anticonvulsants. In this narrative review, we will discuss some of the significant risks and dramatic consequences that are associated with epilepsy: depression, suicide, seizure-related injuries, and mortality, both in adults and in children. Considering the high prevalence of depression among people with epilepsy ….

  3. Where we once thought of SUDEP as a rare & incurable phenomenon, we now understand it as a key driver of premature epilepsy mortality with opportunities for prevention. This session will explore a range of opportunities and interventions – from clinical & basic science approaches to advanced use of technology – that seek to drive the prevention of sudden death in epilepsy.

  4. 16 de dic. de 2015 · Among neurologic disorders in the United States, sudden unexpected death in epilepsy (SUDEP) is the leading cause of lost years of life after stroke. 1 Because the incidence of epilepsy is greatest among the young, SUDEP, along with status epilepticus, accidents, drownings, and suicide, the most common epilepsy-related causes of death, together lead to substantial premature mortality.

  5. 20 de ago. de 2020 · There is significant mortality and morbidity associated with medication-resistant epilepsy, with attendant major impact on physical, psychological, emotional, socioeconomic and other aspects of the lives of persons with epilepsy and their families. Emphasis on these issues is an imperative that is often underappreciated or overlooked, with ...

  6. 25 de nov. de 2023 · Using UK Biobank, we identified 7786 (1.6%) participants with diagnoses of epilepsy and 6,171,803 person-years of follow-up (mean 12.30 years, standard deviation 1.74); 566 patients with previous histories of stroke were excluded.

  7. Epilepsy affects 65 million people worldwide and entails a major burden in seizure-related disability, mortality, comorbidities, stigma, and costs. In the past decade, important advances have been made in the understanding of the pathophysiological mechanisms of the disease and factors affecting its prognosis.