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Hace 2 días · MicroRNA ( miRNA) are small, single-stranded, non-coding RNA molecules containing 21 to 23 nucleotides. [1] . Found in plants, animals and some viruses, miRNAs are involved in RNA silencing and post-transcriptional regulation of gene expression.
Hace 1 día · Long non-coding RNAs (long ncRNAs, lncRNA) are a type of RNA, generally defined as transcripts more than 200 nucleotides that are not translated into protein. They have regulatory functions and are involved in several processes such as the cellular biogenesis of macromolecules, differentiation , gene expression and chromatin remodelling [3] .
Hace 3 días · The RNA world is a hypothetical stage in the evolutionary history of life on Earth, in which self-replicating RNA molecules proliferated before the evolution of DNA and proteins. [1] . The term also refers to the hypothesis that posits the existence of this stage.
Hace 5 días · protein synthesis. DNA in the cell nucleus carries a genetic code, which consists of sequences of adenine (A), thymine (T), guanine (G), and cytosine (C) (Figure 1). RNA, which contains uracil (U) instead of thymine, carries the code to protein-making sites in the cell.
Hace 4 días · It is the messenger between the DNA and the machines that make the proteins—ribosomes. The mRNA transcript is made in the nucleus, where the DNA is located, and then moved to the cytoplasm, where ribosomes are located. The process of reading the mRNA and making a protein is called translation.
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Hace 2 días · Non-coding RNAs were identified using Rfam 39,40, ribosome RNAs (rRNAs) and transfer RNAs (tRNAs) were searched by tRNAscan-SE v2.0 41 and RNAmmer v1.2 42, both with default parameters.
Hace 5 días · RNA is a single-stranded molecule that acts as a messenger, regulates gene expression, and even catalyzes reactions. It’s essential for life and could hold the key to treating diseases. RNA played a crucial role in the early stages of life on Earth and is now being targeted for therapeutic drugs.
