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Hace 3 días · FULL TEXT. PDF. El antígeno carcinoembrionario (CEA) es un marcador tumoral ampliamente empleado en el manejo del cáncer colorrectal, especialmente en el seguimiento de los pacientes resecados con intención curativa. El objetivo de esta revisión es actualizar el rol del CEA en el manejo de los pacientes intervenidos por un ...
Hace 2 días · The Wnt signaling pathway is one of the most ancient and pivotal signaling cascades, governing diverse processes in development and cancer regulation. Within the realm of cancer treatment, genistein emerges as a promising candidate due to its multifaceted modulation of various signaling pathways, including the Wnt pathway. Despite promising preclinical studies, the precise mechanisms ...
Hace 5 días · Colonic adenomas are the predominant precursor lesion to colonic adenocarcinoma and the adenoma-carcinoma sequence is well documented and accepted in international literature. 9 Adenomatous polyps include tubular adenomas, villous adenomas and tubulovillous adenomas. 10 High-risk features in these lesions include size ≥10 mm, villous architecture >25% and the presence of high-grade dysplasia ...
Hace 2 días · This study aimed to explore the expression, function, and mechanisms of TBC1D10B in colon cancer, as well as its potential applications in the diagnosis and treatment of the disease.The expression levels of TBC1D10B in colon cancer were assessed by analyzing the TCGA and CCLE databases. Immunohistochemistry analysis was conducted using tumor and adjacent non-tumor tissues from 68 colon cancer ...
Hace 3 días · The most common form of colon cancer is adenocarcinoma, constituting between 95% and 98% of all cases of colorectal cancer. Other, rarer types include lymphoma, adenosquamous and squamous cell carcinoma. Some subtypes are more aggressive. Immunohistochemistry may be used in uncertain cases. Staging
Hace 1 día · In this study, we demonstrate a spatial biology workflow utilizing Cell DIVE and AIVIA software to map the tumor immune landscape in colon adenocarcinoma. By visualizing 30 biomarkers within a single tissue and performing AI-powered segmentation and phenotyping, we are able to uncover multiple facets of tumor cell aggression.
Hace 5 días · Colon adenocarcinoma, Diagnosis, Treatment, Biomarker. Abstract. In the current study, the role of cell division cycle-associated 8 (CDCA8) in colon adenocarcinoma (COAD) was analyzed through comprehensive expression and methylation analysis, genetic mutation inquiry, and prognostic assessment.
