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Hace 2 días · Ccnd1 and Cdk4/6 were expressed in multiciliated cell precursors (Figs. 1c,d and 2a).During the canonical cell cycle, D-type cyclins activate CDK4/6 to direct the progression from early G1/G0 into ...
Hace 4 días · In addition to supplying cellular energy, mitochondria are involved in other tasks, such as signaling, cellular differentiation, and cell death, as well as maintaining control of the cell cycle and cell growth. Mitochondrial biogenesis is in turn temporally coordinated with these cellular processes.
Hace 2 días · Eukaryotes have a life cycle that involves sexual reproduction, alternating between a haploid phase, where only one copy of each chromosome is present in each cell, and a diploid phase, with two copies of each chromosome in each cell.
Hace 1 día · Cell cycle experiments were conducted to analyse the mechanism of proliferation inhibition and cell death in six cell types by almonertinib and alflutinib. The results are presented in Figs. 2 , 3 F, H, N, P, 4 H, J, P, R and Supplementary Fig. 8–10F, H, K, P. Treatment with almonertinib and alflutinib increased cell aggregation in the G1 phase and decreased cells in the S and G2/M phases.
Hace 2 días · e24122 Background: The relationship of vitamin D (VD) with cancer is controversial. Its antiproliferative function by inhibiting the cell cycle has been described, as well as its characteristics as an inhibitor of angiogenesis, inducer of apoptosis and its ability to reduce inflammation, invasion and metastasis. Deficiency of this vitamin is very prevalent, affecting 40% of the population ...
Hace 2 días · BHLHE41 deficiency promoted cell proliferation, accelerated cell cycle progression, and increased cell migration and invasion in BCa cells. A Western blot analysis of BHLHE41 protein level in 5637 and T24 cells stably infected with lentivirus containing specific shRNA targeting BHLHE41 (shBHLHE41) and control shRNA (shNC), and quantitative analysis.
Hace 3 días · Cell cycle analysis was performed using a Cell Cycle Detection Kit (Beyotime, Shanghai, China) according to the manufacturer. Briefly, cells were washed with cold PBS and fixed in 75% pre-cooled ethanol at 4°C overnight.
