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  1. Sir Augustus Frederick d'Este, KCH (13 January 1794 – 28 December 1848) was a relative of the British royal family and the earliest recorded person for whom a definite diagnosis of multiple sclerosis can be made.

  2. Sir Augustus Frederick D’Esté (1794–1848) was an illegitimate royal child, a bachelor, an active member of the Aborigines Protection Society, and the earliest known person diagnosed with multiple sclerosis. For 24 years D’Esté kept a diary, currently held in the Royal College of Physicians’ archives, which documents what he called ‘my case’.

  3. Augustus d'Este fue la primera persona en ser diagnóstica con esclerosis múltiple. Sus síntomas comenzaron a los 28 años de edad con una repentina pérdida transitoria de la vista tras el funeral de un amigo.

  4. 17 de oct. de 2009 · The personal diary of Sir Augustus d’Esté, born 1794 grandson of King George III of England, reveals a medical history strongly suggesting that Augustus suffered from multiple sclerosis (MS). It could well be the first record of a person having this disease.

  5. Augusto, duque de Sussex (August Federick; Londres; 27 de enero de 1773-Londres, 21 de abril de 1843), fue un príncipe del Reino Unido y miembro de la familia real británica desde su nacimiento, como el noveno de los quince hijos de los reyes Jorge III del Reino Unido y Carlota, hasta su muerte.

  6. The first case history of multiple sclerosis: Augustus d’Esté (1794–1848) AbstractThe personal diary of Sir Augustus d’Esté, born 1794 grandson of King George III of England, reveals a medical history strongly suggesting that Augustus suffered from multiple sclerosis (MS).….

  7. It is a singular fact that the earliest account of the symptoms and clinical history of multiple sclerosis was written by Sir Augustus d'Este, a grandson of King George III of England, who kept a personal diary and record of his disease between 1822 and 1848.