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Paul Lawrence Modrich (Ratón, 13 de junio de 1946) es profesor de la cátedra James B. Duke de bioquímica en la Universidad de Duke e investigador en el Howard Hughes Medical Institute. Recibió su Ph.D. por la Universidad de Stanford en 1973. Previamente había estudiado en el MIT.
Paul Lawrence Modrich (born June 13, 1946) is an American biochemist, James B. Duke Professor of Biochemistry at Duke University and Investigator at the Howard Hughes Medical Institute. He is known for his research on DNA mismatch repair. Modrich received the Nobel Prize in Chemistry 2015, jointly with Aziz Sancar and Tomas Lindahl.
Professor Emeritus of Biochemistry. Professor of Chemistry. Member of the Duke Cancer Institute. Adjunct Faculty and Faculty Emeritus. 156A Nanaline H Duke, Durham, NC 27708. Box 3711 Med Ctr, Durham, NC 27710. +1 919 681 8818. modrich@biochem.duke.edu.
Paul Modrich. The Nobel Prize in Chemistry 2015. Born: 13 June 1946, Raton, NM, USA. Affiliation at the time of the award: Howard Hughes Medical Institute, Durham, NC, USA; Duke University School of Medicine, Durham, NC, USA. Prize motivation: “for mechanistic studies of DNA repair” Prize share: 1/3. Life.
Overview. Paul Modrich, James B. Duke Professor of Biochemistry, was awarded the 2015 Nobel Prize for Chemistry along with Tomas Lindahl of the Francis Crick Institute and Clare Hall Laboratory in the UK, and Aziz Sancar of University of North Carolina, Chapel Hill, for mechanistic studies of DNA repair.
9 de may. de 2024 · Paul Modrich is an American biochemist who discovered mismatch repair, a mechanism by which cells detect and correct errors that are introduced into DNA during DNA replication and cell division. Modrich was among the first to show that a common form of inherited colorectal cancer is due to.
Paul L. Modrich | Scholars@Duke profile: Publications. James B. Duke Distinguished Professor Emeritus of Biochemistry. Biochemistry. modrich@biochem.duke.edu. Box 3711 Med Ctr, Durham, NC 27710. 156A Nanaline H Duke, Durham, NC 27708. Selected Publications. Human MutLγ, the MLH1-MLH3 heterodimer, is an endonuclease that promotes DNA expansion.
