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Deranged Physiology is a free online resource for Intensive Care medicine, created and maintained by Alex Yartsev. It serves as an unofficial study guide for trainees of the College of Intensive Care Medicine preparing for their exams.
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Cellular physiology questions with official answers and...
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SKELETAL MUSCLE ORGANIZATION. Each muscle is a bundle of fibers. Each fiber is a long, multinucleated single cell. Each fiber is surrounded by a SARCOLEMMA- the cell membrane. There are NO SYNCYTIAL BRIDGES between the cells. When one cell goes off, the others don’t follow. TRANSVERSE TUBULES: T-tubules, invaginations of.
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Basic Physics of Mechanical Ventilation: . ventilator is just a sophisticated leaf blower. It is essentially a FLOW DELIVERY MECHANISM. Inside, there is a precisely controlled turbine. It spins and generates a flow. The CONTROL variables: . Volume. Flow = Time . FLOW. VOLUME. PRESSURE. Volume = Flow x Time.
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Together with DCS, damage control resuscitation (DCR) is the cornerstone of the treatment of severely injured and severely physiologically deranged patients. DCR is fundamental in OA management and influences the outcome of the patient. DCR includes several actions taken in the Intensive care Unit (ICU) setting, such as volume resuscitation, revers...
OA management consists in intentionally leaving the fascial edges of the paired rectus abdominus muscles unapproximated. In the so-called laparostomy, several methods have been described to temporary close the abdomen. In loose packing, the defect is closed by standard wound dressing. In mesh-mediated techniques, an absorbable or nonabsorbable mesh...
DCS is a strong arrow in the bow for the surgeon facing trauma and nontrauma patients with a deranged physiology, severe injuries, or critical illness. In these life-threatening situations, OA is dramatically effective. Guidelines clearly report all the indications to perform DCS and OA. However, translating these indications into clinical practice...
In the DCS management, always apply a DCR: volume resuscitation, reversal of coagulopathy, and correction of acidosis.In trauma patients, stop the lethal triad as soon as possible.Ensure to routinely measure the abdominal pressure.If possible, leave the abdomen open with NPWT and CFT.DCS is a strong arrow in the bow for the surgeon facing trauma and nontrauma patients with a deranged physiology, severe injuries, or critical illness. In these life-threatening situations, OA is d...Several indications to DCS have been reported, but some of those have not reported a clear benefit. Therefore, guidelines should be followed and the indication to DCS and OA should be tailored to e...DCR is the cornerstone of the treatment of severely injured and severely physiologically deranged patients. Multidisciplinary management is of utmost importance for these patients.When performing OA, several TAC techniques have been described. Two meta-analyses report that NPWT with CFT is the most effective in terms of fascial closure.1. According to international guidelines, a proper indication to DCS and OA in trauma patients is:2. According to international guidelines, a proper indication to DCS and OA in a peritonitis patient undergoing surgery is:3. In the damage control resuscitation, how often should intra-abdominal pressure be measured?4. Which is the most effective TAC technique in terms of fascial closure?Deranged Physiology is a very slowly growing online resource for information regarding intensive care medicine, as well as an exploration of human physiology, with frequent irrelevant digressions.
Mechanisms of Tolerance and Tachyphylaxis | Deranged Physiology - Free download as PDF File (.pdf), Text File (.txt) or read online for free. Scribd is the world's largest social reading and publishing site.
As evidenced by the work of Russotto et al, appreciation of deranged physiology, in addition to anticipation of difficult anatomic airways, are imperative to navigate these encounters while minimizing harm.3 In their observational study, the authors analyzed 2964 con-secutive adult patients who underwent endotracheal intubation in intensive care...
