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  1. What the liver does. Your liver works around the clock to keep you healthy. Among its most important jobs are: Producing important substances. Your liver continually produces bile. This is a chemical that helps turn fats into energy that your body uses. Bile is necessary for the digestive process. Your liver also creates albumin.

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    • Overview
    • Structure
    • Functions
    • Regeneration
    • Diseases
    • Health
    • Summary

    The liver is the largest solid organ in the body. It carries out over 500 tasks and plays an essential role in digestion. The roles of the liver include detoxification, protein synthesis, and the production of chemicals that help digest food.

    It is part of the digestive system.

    A person’s liver is in the upper right section of the abdomen and sits below the diaphragm. It typically weighs around 3 pounds, but this can vary between people. The skin is the only organ heavier and larger than the liver.

    The liver is roughly triangular and consists of two lobes: a larger right lobe and a smaller left lobe. The falciform ligament separates the lobes. This ligament is a band of tissue that keeps the liver anchored to the diaphragm.

    A layer of fibrous tissue called Glisson’s capsule covers the outside of the liver. The peritoneum, a membrane that forms the lining of the abdominal cavity, then covers this.

    This helps hold the liver in place and protects it from physical damage.

    The liver is a gland that has many functions in the body. It is difficult to give a precise number, but it may have more than 500 distinct roles.

    The major functions of the liver include:

    •Bile production: Bile helps the small intestine break down and absorb fats, cholesterol, and some vitamins. Bile consists of bile salts, cholesterol, bilirubin, electrolytes, and water.

    •Absorbing and metabolizing bilirubin: The breakdown of hemoglobin forms bilirubin. The liver or bone marrow stores iron released from hemoglobin, which makes the next generation of blood cells.

    •Supporting blood clots: Vitamin K is necessary to create coagulants that help clot the blood. Bile is essential for vitamin K absorption and forms in the liver. The liver must produce enough bile to make clotting factors.

    •Fat metabolization: Bile breaks down fats and makes them easier to digest.

    Because of the importance of the liver and its functions, evolution has ensured that it can regrow rapidly as long as it is kept healthy. All vertebrates, from fish to humans, have the ability to regrow the liver.

    The liver is the only visceral organ that can regenerate. It can regenerate completely, as long as a minimum of about 25% of the tissue remains. The liver can regrow to its previous size and ability without any loss of function during the growth process.

    Removal of two-thirds of the liver in mice causes the remaining liver tissue to regrow to its original size and restore function within 7—10 days. In humans, the process takes slightly longer, but regeneration can still occur in 8—15 days. Researchers suggest surgical removal of the right or left lobe of the liver results in complete restoration of the liver mass after 3 months, while maximum cellular activity happens 7 to 10 days after the procedure.

    Over the following few weeks, the new liver tissue becomes indistinguishable from the original tissue.

    A number of compounds are responsible for liver regeneration, including growth factors and cytokines. Some of the most important compounds in the process appear to be but are not limited to:

    •hepatocyte growth factor

    An organ as complex as the liver can experience a range of problems. A healthy liver functions very efficiently. However, the consequences can be dangerous or even fatal in a diseased or malfunctioning liver.

    Examples of liver disease include:

    •Fascioliasis: The parasitic invasion of a worm, known as a liver fluke, causes this condition. The liver fluke can lie dormant in the liver for months or even years. Fascioliasis is a tropical disease.

    •Cirrhosis: This sees scar tissue replace liver cells in a process known as fibrosis. Toxins, alcohol, and hepatitis are some of the many factors that cause this condition. Eventually, fibrosis can lead to liver failure because the functionality of liver cells becomes destroyed.

    •Hepatitis: Hepatitis is the name given to a general infection of the liver, and viruses, toxins, or an autoimmune response can cause it. An inflamed liver characterizes this condition. In many cases, the liver can heal itself, but liver failure can occur in serious cases.

    •Alcoholic liver disease: Drinking too much alcohol over long periods can cause liver damage.

    Below are some recommendations from the American Liver Foundation to help keep the liver working as it should:

    •Diet: As the liver is responsible for digesting fats, consuming too many can overwork the organ and disturb it from other tasks. This also has links to fatty liver disease.

    •Moderate alcohol ingestion: Avoid consuming more than two drinks at a time. Drinking too much alcohol causes cirrhosis of the liver over time.

    •Avoiding illicit substances: Illicit substances can overload the liver with toxins. Avoiding these substances can allow the liver to perform its necessary functions without impediment.

    •Caution when mixing medications: Some prescription drugs and natural remedies can interact negatively. Mixing drugs with alcohol puts significant pressure on the liver.

    •Protection against airborne chemicals: Airborne chemicals can cause liver damage. When painting or using strong cleaning or gardening chemicals, the area should be well ventilated, and people should wear a mask.

    The liver is the largest solid organ in the human body. It is part of the digestive system and plays an essential role in removing toxins from the blood, metabolizing nutrients, and immune function.

  2. All the blood leaving the stomach and intestines passes through the liver. The liver processes this blood and breaks down, balances, and creates the nutrients and also metabolizes drugs into forms that are easier to use for the rest of the body or that are nontoxic. More than 500 vital functions have been identified with the liver.

  3. 30 de oct. de 2023 · The liver is a large organ found in the upper right quadrant of the abdomen. It is a multifunctional accessory organ of the gastrointestinal tract and performs several essential functions such as detoxification, protein synthesis, bile production and nutrient storage to name only a few.

  4. 9 de ago. de 2021 · The liver has many functions, but its main job within the digestive system is to process the nutrients absorbed from the small intestine. Bile from the liver secreted into the small intestine also plays an important role in digesting fat and some vitamins.

  5. 1 de may. de 2023 · The liver is a critical organ in the human body that is responsible for an array of functions that help support metabolism, immunity, digestion, detoxification, vitamin storage among other functions. It comprises around 2% of an adult's body weight.

  6. 6 de nov. de 2017 · The liver is critical for digestive absorption and performs uptake, synthesis, packaging, and secretion of lipids and lipoproteins. The liver's biliary synthesis and secretion system enables efficient absorption of lipid from digestion.