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This review summarizes our current knowledge of disease pathology and highlights potential druggable pathways. Aortic valve stenosis (AVS) is the most common acquired heart valve disease in the western world. 1, 2 Its prevalence is >2% in patients >60 years of age. 3 When symptomatic, the 2-year mortality rate of severe AVS is around 50%. 4, 5.
- Philip Roger Goody, Mohammed Rabiul Hosen, Dominik Christmann, Sven Thomas Niepmann, Andreas Zietzer...
- 2020
16 de abr. de 2023 · Author Information and Affiliations. Last Update: April 16, 2023. Go to: Objectives: Identify the etiology of aortic stenosis. Outline the appropriate evaluation of aortic stenosis. Review the indications for different types of management options available for aortic stenosis.
- Sai Harika Pujari, Pradyumna Agasthi
- 2023/04/16
- Mayo Clinic, Mayo Clinic Rochester
Higher baseline severity of aortic stenosis is associated with faster progression. Bubble plot and meta-regression shows relationship between baseline aortic stenosis severity and rate of progression. MG = mean gradient. This study provides valuable data on the average echocardiography-based hemodynamic progression.
9 de abr. de 2024 · Calcific aortic valve disease: not simply a degenerative process: a review and agenda for research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group. Executive summary: Calcific aortic valve disease-2011 update.
- Neelakantan Saikrishnan, Gautam Kumar, Fadi J. Sawaya, Stamatios Lerakis, Ajit P. Yoganathan
- 2014
21 de ago. de 2014 · Valvular aortic stenosis is a progressive disease in which the end stage is characterized by obstruction of left ventricular outflow, resulting in inadequate cardiac output, decreased exercise...
- Catherine M. Otto, Bernard Prendergast
- 2014
5 de mar. de 2021 · Summary of clinical practice guidelines and recommendations on aortic stenosis management. AS, aortic stenosis; HFrEF, heart failure with reduced ejection fraction; LV, left ventricle; MDT, multidisciplinary team; SAVR, surgical aortic valve replacement; TAVI, transcatheter aortic valve replacement.
Abstract. Aortic stenosis (AS) is the most common valvular heart disease in Europe and North America requiring a surgical or interventional treatment. Due to demographic changes with an aging population the burden of valvular heart diseases and especially the importance of aortic stenosis (AS) will be growing in future.
