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14 de jul. de 2023 · Fracture healing in a mouse model of Hajdu–Cheney-Syndrome with high turnover osteopenia results in decreased biomechanical stability | Scientific Reports. Article. Open access. Published: 14...
16 de nov. de 2021 · The influence of M-CSF on fracture healing in a mouse model. Sci Rep 11, 22326 (2021). https://doi.org/10.1038/s41598-021-01673-w. Download citation. Received: 23 April 2021. Accepted: 25...
- Julia Starlinger, Kambiz Sarahrudi, Mathias Kecht, Florian Koerbler, Peter Pietschmann, Seyedhossein...
- 2021
4 de abr. de 2016 · Although the bone structure of mice and humans differs considerably, the process of fracture healing is very similar, making the mouse a good model for fracture-healing research [21, 22]. In both species, initial tissue damage and rupture of blood vessels lead to activation of inflammatory cells.
- Melanie Haffner-Luntzer, Anna Kovtun, Anna E. Rapp, Anita Ignatius
- 2016
10 de feb. de 2023 · In this study, we employed a detailed molecular analysis of fracture healing in a wild-type mouse model to serve as a blueprint useful for diagnosing molecular dysregulation throughout the healing process.
In recent years, mice have become increasingly pop-ular as a model organism for fracture healing research. The benefits of mice are the possibility of genetic modification, the availability of clinically relevant disease models, low costs, easy handling, short breeding cycles and fast regeneration.
- Melanie Haffner-Luntzer, Anna Kovtun, Anna E. Rapp, Anita Ignatius
- 2016
1 de oct. de 2020 · Article 21 April 2021. Individualized cyclic mechanical loading improves callus properties during the remodelling phase of fracture healing in mice as assessed from time-lapsed in vivo...
Proper fixation of a closed femoral fracture is paramount for the success of union and creating a reproducible method to study fracture healing. Stiffness and rigidity of the fracture fixation directly correlates to the amount of motion within the fracture site and developing callus.
