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1 de oct. de 2018 · James P. Allison and Tasuku Honjo. for their discovery of cancer therapy by inhibition of negative immune regulation. SUMMARY. Cancer kills millions of people every year and is one of humanity’s greatest health challenges.
1 de oct. de 2018 · La Asamblea Nobel del Instituto Karolinska de Estocolmo les otorgó el Nobel de Medicina al estadounidense James P. Allison y el japonés Tasuku Honjo por haber descubierto una terapia...
The Nobel Prize in Physiology or Medicine 2018 was awarded jointly to James P. Allison and Tasuku Honjo "for their discovery of cancer therapy by inhibition of negative immune regulation".
- Early Excitement
- Releasing The Brakes
- Obvious Choices
- Combination Therapy
Allison is in New York for an immunology conference, and was awoken at 5.30 by a call from his son delivering the good news. By 6.30, colleagues were banging on the door of his hotel room bearing champagne for an impromptu party. The Nobel Committee only reached him some time after that. “It still hasn’t completely dawned on me,” said Allison, at a...
“Allison’s and Honjo’s discoveries have added a new pillar in cancer therapy. It represents a completely new principle, because unlike previous strategies, it is not based on targeting the cancer cells, but rather the brakes — the checkpoints — of the host immune system”, said Klas Kärre, a member of the Nobel Committee and an immunologist at the K...
Immunologist Jerome Galon of the French national biomedical research agency, INSERM, in Paris, was not surprised by the committee’s decision to award the prize to Honjo and Allison. “I think they really deserve it,” he says. “You can always multiply and have many other people, but these are the obvious two first choices.” He adds that the prize ref...
A major draw, says Galon, is the potential of these drugs to lengthen patients’ lives by years, rather than just weeks or months. But only a fraction of patients experiences such dramatic responses, and researchers are racing to boost those numbers by combining checkpoint inhibitors with each other and with other treatments. “The huge benefit in co...
- Heidi Ledford, Holly Else, Matthew Warren
- 2018
The Nobel Prize in Physiology or Medicine 2018 was awarded jointly to James P. Allison and Tasuku Honjo "for their discovery of cancer therapy by inhibition of negative immune regulation"
18 de ene. de 2017 · The 2018 Nobel Prize in Physiology or Medicine was awarded to James P. Allison and Tasuku Honjo “for their discovery of cancer therapy by inhibition of negative immune regulation”.
1 de oct. de 2018 · El Instituto Karolinska de Estocolmo, en Suecia, anunció que el estadounidense James P. Allison y el japonés Tasuku Honjo ganaron el premio Nobel de Medicina 2018 por sus revolucionarios ...
