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8 de ene. de 2021 · Purpose: Stereotactic body radiation therapy (SBRT) has demonstrated clinical benefits for patients with metastatic and/or unresectable cancer. Technical considerations of treatment delivery and nearby organs at risk can limit the use of SBRT in large tumors or those in unfavorable locations.
- Sai Duriseti, James Kavanaugh, Sreekrishna Goddu, Alex Price, Nels Knutson, Francisco Reynoso, Jeff ...
- 2021
22 de oct. de 2019 · Spatially Fractionated Radiation therapy (SFRT) has a history of over 100 years. The principle of SFRT is distinctive from the standard radiation approaches, as it treats the total tumor with a non-uniform dose, effectively treating the tumor while staying within normal tissue tolerance of the surrounding structures.
- Weisi Yan, Mohammad K. Khan, Xiaodong Wu, Charles B. Simone, Jiajin Fan, Eric Gressen, Xin Zhang, Ch...
- 10.1016/j.ctro.2019.10.004
- 2020
- 2020/01
Spatially fractionated radiotherapy (SFRT) includes historical grid therapy approaches but more recently encompasses the controlled introduction of one or more cold dose regions using intensity modulation delivery techniques.
2 de may. de 2024 · La radioterapia mediante fraccionamiento espacial (SFRT) es una técnica de radioterapia que permite administrar dosis de radiación relativamente altas, aunque variables, a un tumor de grandes dimensiones, protegiendo, al mismo tiempo, los órganos sanos circundantes.
11 de abr. de 2024 · Spatially Fractionated Radiotherapy (SFRT) has demonstrated promising potential in cancer treatment, combining the advantages of reduced post-radiation effects and enhanced local control...
8 de jun. de 2021 · Spatially fractionated radiation therapy (SFRT) intentionally delivers a nonuniform dose distribution to the gross tumor volume, and it represents a crossover from the laboratory to the clinic. 66 The radiobiologic rationale for SFRT is built on hypotheses and research suggesting specific molecular and cellular bystander mechanisms ...
5 de may. de 2019 · SFRT delivers high doses of radiation without exceeding the tolerance of critical structures, particularly skin, by limiting the volume of irradiated tissue. Early-phase clinical studies show excellent response rates, often with dramatic and rapid resolution of large tumors.
