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  1. Sir Augustus Frederick d'Este, KCH (13 January 1794 – 28 December 1848) was a relative of the British royal family and the earliest recorded person for whom a definite diagnosis of multiple sclerosis can be made. He was the only son of Prince Augustus Frederick, Duke of Sussex and his wife Lady Augusta Murray.

  2. Sir Augustus Frederick D’Esté (1794–1848) was an illegitimate royal child, a bachelor, an active member of the Aborigines Protection Society, and the earliest known person diagnosed with multiple sclerosis. For 24 years D’Esté kept a diary, currently held in the Royal College of Physicians’ archives, which documents what he called ...

  3. 17 de oct. de 2009 · Abstract. The personal diary of Sir Augustus d’Esté, born 1794 grandson of King George III of England, reveals a medical history strongly suggesting that Augustus suffered from multiple sclerosis (MS). It could well be the first record of a person having this disease.

    • Anne Marie Landtblom, Patrik Fazio, Sten Fredrikson, Enrico Granieri
    • 2010
  4. Abstract. The personal diary of Sir Augustus dEste ́, born 1794 grandson of King George III of England, reveals a medical history strongly suggesting that Augustus suffered from multiple sclerosis (MS). It could well be the first record of a person having this disease.

    • Anne Marie Landtblom, Patrik Fazio, Sten Fredrikson, Enrico Granieri
    • 2010
  5. The first case history of multiple sclerosis: Augustus d’Esté (1794–1848) AbstractThe personal diary of Sir Augustus d’Esté, born 1794 grandson of King George III of England, reveals a medical history strongly suggesting that Augustus suffered from multiple sclerosis (MS).….

  6. The Case of Augustus d'Este (1794-1848): The First Account of Disseminated Sclerosis: (Section of the History of Medicine). Firth D. Proceedings of the Royal Society of Medicine , 01 May 1941, 34 (7): 381-384. DOI: 10.1177/003591574103400703 PMID: 19992339 PMCID: PMC1998243. Free to read. Share this article. Abstract. No abstract provided.

  7. Two figures stand out: the high-born aristocrat, Augustus D'Este and his diaries of the early 19th century and the courageous if histrionic Bruce Frederick Cummings in the early 20th century.