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Sepsis: pathophysiology and clinical management. British Medical Journal 2016. La sepsis es una afección grave que se produce cuando el sistema inmunitario del cuerpo responde de manera extrema a una infección, lesionando sus propios tejidos y órganos.
La sepsis es una urgencia médica y si no se diagnostica y trata de forma temprana, puede ocasionar daño irreversible a los tejidos, choque séptico, insuficiencia orgánica múltiple y poner en riesgo la vida.
La sepsis, sepsis severa y shock séptico son condiciones que conllevan alta morbilidad y mortalidad, por esto, es deseable para los médicos de atención primaria y de emergencias, poder definir "sepsis" como se definen los criterios de otras patologías como la endocarditis bacteriana, con criterios de alta sensibilidad y sobretodo alta ...
- Elsa R Neira-Sanchez, Germán Málaga
- 2016
- Key Facts
- Overview
- Who Is at Risk?
- Signs and Symptoms
- Prevention
- Treatment
- Sustainable Development Goals
- Who Response
Sepsis is one of the most frequent causes of death worldwide, but there are challenges in collecting reliable data at the population level (1).From data published in 2020, there were 48.9 million cases and 11 million sepsis-related deaths worldwide, representing 20% of all global deaths (2).Almost half (20 million) of all estimated sepsis casesworldwide occurred in children under 5 years of age.For every 1000 hospitalized patients, an estimated 15 patients will develop sepsis as a complication of receiving health care.Sepsis is a life-threatening condition that happens when the body’s immune system has an extreme response to an infection, causing organ dysfunction (4). The body’s reaction causes damage to its own tissues and organs and it can lead to shock, multiple organ failure and sometimes death, especially if not recognized early and treated promptly. Sepsi...
Anyone affected by an infection, severe injury, or serious non-communicable disease can progress to sepsis but vulnerable populations are at higher risk (6,7) including: 1. older persons 2. pregnant or recently pregnant women 3. neonates 4. hospitalized patients 5. patients in intensive care units 6. people with weakened immune systems (for example...
Sepsis is a medical emergency. It can cause different signs and symptoms at different times. People who think they may have sepsis should seek medical care right away. Common signs and symptoms include: 1. fever or low temperature and shivering 2. confusion 3. difficulty breathing 4. clammy and sweaty skin 5. extreme body pain or discomfort 6. high...
Sepsis can be prevented by treating infections early and through good hygiene at home and in healthcare settings. The best way to reduce the risk of sepsis is to avoid infections. Steps include: 1. good personal hygiene, like washing hands and preparing food safely 2. avoiding unclean water or unsanitary toilets 3. getting vaccines recommended by l...
Treatment for sepsis is most effective when started early. Health workers watch for concerning signs and use tests to diagnose sepsis. They will then work to find the source of the infection. Early use of antimicrobials to treat bacteria, parasites, fungus or viruses is essential to improve outcomes from sepsis. Low blood pressure is treated by int...
Sepsis is a significant cause of maternal, neonatal and child mortality. Consequently, combating sepsis will contribute to achievement of Sustainable Development Goals (SDGs) targets 3.8 on quality of care, and 3.1 and 3.2 by improving mortality rates in these vulnerable populations. Sepsis can also ultimately lead to death in patients affected by ...
To combat this important global health threat, WHO responded with a WHO Secretariat Report and, in May 2017, the Seventieth World Health Assembly adopted Resolution WHA70.7 on improving the prevention, diagnosis and clinical management of sepsis. The key pillars of Resolution WHA70.7 are to: 1. develop WHO guidelines on the clinical management of s...
La sepsis es un síndrome clínico de disfunción de órganos potencialmente letal causada por una respuesta desregulada a la infección. En el shock séptico hay una reducción crítica de la perfusión tisular; puede producirse una insuficiencia aguda multiorgánica, que afecta los pulmones, los riñones y el hígado.
La sepsis se define como una disfunción multiorgánica secundaria a un proceso infeccioso que puede progresar a choque séptico con aumento en el riesgo de mortalidad. Recientes actualizaciones de Sepsis nos permiten realizar un diagnóstico precoz y abordaje terapéutico oportuno con disminución de la morbimortalidad a corto y mediano plazo.
13 de nov. de 2023 · ¿Qué es la sepsis? La sepsis es la respuesta abrumadora y extrema de su cuerpo a una infección. La sepsis es una emergencia médica que puede ser mortal. Sin un tratamiento rápido, puede provocar daños en los tejidos, falla orgánica e incluso la muerte. ¿Qué causa la sepsis?
