St. James' Roman Catholic Church is located at 32 James Street between St. James Place and Madison Street in the Two Bridges neighborhood of Lower Manhattan, New York City. It is the second oldest Roman Catholic building in the city, built in 1835–1837 of fieldstone, with a pair of Doric columns flanking the entrance.
Named in honor of Anthony of Padua, it falls within the jurisdiction of the Roman Catholic Diocese of Wilmington and is operated by the Oblates of St. Francis de Sales. It is situated in Wilmington's Little Italy neighborhood, where the parish includes St. Anthony's School (adjacent to the church) and Padua Academy.
The leader of the Roman Catholic Church is called the Pope, which literally means "father". Catholics say Jesus Christ established the Catholic Church, and appointed the first Pope, a disciple of his named Saint Peter, to lead all Christians. Over the last 2,000 years, different Popes have led the church.