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  1. Combined drug intoxication (CDI), or multiple drug intake (MDI), is a cause of death by drug overdose from poly drug use, often implicated in polysubstance dependence. Deaths by combined drug intoxication are relatively rare (one in several million).

  2. Combined drug intoxication use often carries with it more risk than use of a single drug, due to an increase in side effects, and drug synergy. The potentiating effect of one drug on another is sometimes considerable and here the licit drugs and medicines – such as alcohol , nicotine and antidepressants – have to be considered in ...

  3. Specialty. Psychiatry, narcology, addiction medicine. Substance intoxication is a transient condition of altered consciousness and behavior associated with recent use of a substance. [1] It is often maladaptive and impairing, but reversible. [2]

  4. 6 de feb. de 2024 · Combined drug intoxication is a form of substance use that involves taking two or more drugs simultaneously. Examples include mixing: prescription drugs (legally or illegally obtained) over-the-counter drugs. herbal mixtures. Generally, combining substances at the same time tends to have stronger effects than using just one substance.

  5. 20 de may. de 2015 · Combination therapies exploit the chances for better efficacy, decreased toxicity, and reduced development of drug resistance and owing to these advantages, have become a standard for the treatment of several diseases and continue to represent a promising approach in indications of unmet medical need.

    • Julie Foucquier, Mickael Guedj
    • 10.1002/prp2.149
    • 2015
    • 2015/06
  6. Combined drug intoxication (CDI) happens when a person ingests multiple drugs at one time. Drug users may consume multiple substances on accident—for example, in the case of laced drugs—or intentionally, to heighten their effects. The latter case is especially true for those struggling with addiction.

  7. 21 de ago. de 2023 · Infographics. Latest Data: Combination Drug Use Increases Overdoses. Substance Use. Published on: August 21, 2023. 74% of cocaine deaths. involved a synthetic opioid. These interactive graphics report on the emerging trends in overdose deaths, as well as evidence-based strategies for reducing overdoses.