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Chiconquiauitl (Chiconquiauhtzin) se convierte en tlatoani (gobernante) del altépetl (ciudad-estado) de Azcapotzalco en el Valle de México. Se compone Semejança del mundo, considerado el primer atlas geográfico de la historia, en castellano.
Year 1222 was a common year starting on Saturday (link will display the full calendar) of the Julian calendar.
- Chemistry
- Physical-Chemical Properties
- History
- Odor
- Environmental Data
- Human Health
- Regulatory and Safety Status
Galaxolide is the trade name from International Flavors & Fragrances Inc. (IFF) for the fragrance material with CAS Registry Number1222-05-5 and CAS chemical name cyclopenta(g)-2-benzopyran, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-. Galaxolide is also known by its IUPAC name 4,6,6,7,8,8-hexamethyl-1,3,4,6,7,8-hexahydro-cyclopenta[g]-isochromen...
Galaxolide is a mixture of isomers. It has chiral centers at carbon atom 4 and 7. The isomers are (4R,7R), (4R,7S), (4S,7S) and (4S, 7R). Galaxolide has a molecular formula of C18H26O and a molecular weight of 258.4 g/mol. At room temperature, it occurs as a highly viscous liquid. Its melting point is -20 °C and its boiling point is estimated to be...
Galaxolide was discovered at IFF in the 1960s, by Heering and Beets. It was first synthesized in 1965 and its discovery was mainly due to the work by Beets on the osmophoric group of the polycyclic musks, where they tried to improve existing synthetic musks by making them more stable and hydrophobic
Galaxolide has become the key synthetic musk ingredient belonging to the polycyclic musk group as defined by the International Fragrance Association (IFRA). Its odor is described as a “clean”, sweet, floral, woody musk, Research has shown that it is in particular the (4S,7R) and the (4S, 7S) forms of galaxolide that are the most powerful musk notes...
Galaxolide has a measured bioconcentration factor (BCF) in fish in a range of 600-1600 and a log octanol-water partition coefficient (Log Kow) of around 5.5 (5.3 – 5.9). Given its lack of bioaccumulation and toxicity, the EU determined that galaxolide does not meet the criteria for being a substance classified as Persistent, Bioaccumulative and Tox...
Galaxolide is not an irritant, not toxic, not a CMR substance nor a sensitizer.Based on test data, the EU Scientific Committee for Consumer Safety included galaxolide in their proposal for extending the allergen information on cosmetic products as it claims to have seen only up to 100 individual cases worldwide in the last several decades who have ...
In 2002, The Scientific Committee on Cosmetics and Non-Food Products (SCCNFP), the expert scientific board that advises the European Commission on human health issues, reviewed the human safety of galaxolide, when used in cosmetic products, and issued a final opinion on 17 September 2002.The SCCNFP stated that "...HHCB [galaxolide] can be safely us...
- C₁₈H₂₆O
- 258.405 g·mol−1
- 214-946-9
- .mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}1222-05-5
The 1220s was a decade of the Julian Calendar which began on January 1, 1220, and ended on December 31, 1229. Events. 1220. By place. Fifth Crusade. July – The Crusaders, led by the Knights Hospitaller, raid Burlus, located in the Nile Delta in Egypt.
The Golden Bull of 1222 was a golden bull, or edict, issued by Andrew II of Hungary. King Andrew II was forced by his nobles to accept the Golden Bull (Aranybulla), which was one of the first examples of constitutional limits being placed on the powers of a European monarch. [1]
- 1222
- Andrew II of Hungary
- confirmation of the rights of nobility
1224 ( MCCXXIV) fue un año bisiesto comenzado en lunes del calendario juliano . Acontecimientos. San Francisco de Asís (Giovanni Francesco Bernardone) recibe los estigmas. Introducción de la máquina de hilar en Francia e Italia.
La Bula de Oro (en húngaro: Aranybulla) fue un documento sancionado en 1222 por el rey Andrés II de Hungría por consecuencia de la presión de los señores feudales húngaros que cada vez tenían más poder. Fue uno de los primeros ejemplos de limitación constitucional de poderes de una monarquía europea. 1 .
