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  1. Anne Seymour, Duchess of Somerset (née Stanhope; Before 1512 – 16 April 1587) was the second wife of Edward Seymour, 1st Duke of Somerset (c. 1500–1552), who held the office of lord protector during the first part of the reign of their nephew King Edward VI.

  2. Anne (6 February 1665 – 1 August 1714) reigned as Queen of England, Scotland and Ireland from 8 March 1702 until 1 May 1707. On 1 May 1707, under the Acts of Union, the kingdoms of England and Scotland united as a single sovereign state known as Great Britain. Anne continued to reign as Queen of Great Britain and Ireland until her death.

  3. John Beaufort (1371/1373–1410) was the eldest son from John of Gaunt's marriage to Katherine Swynford.He was created Earl of Somerset on 10 February 1397; on 9 September 1397, following his marriage to Margaret Holland, daughter of Thomas Holland, 2nd Earl of Kent, he was promoted to Marquess of Somerset, and a few weeks later on 29 September 1397 he was created also Marquess of Dorset.

  4. Born in the Duchy of Lorraine into the House of Valois-Anjou, Margaret was the second eldest daughter of René, King of Naples, and Isabella, Duchess of Lorraine. She was one of the principal figures in the series of dynastic civil wars known as the Wars of the Roses and at times personally led the Lancastrian faction.

  5. Thomas Seymour, 1st Baron Seymour of Sudeley, KG, PC (c. 1508 – 20 March 1549) was a brother of Jane Seymour, the third wife of King Henry VIII. With his brother, Edward Seymour, 1st Duke of Somerset and Lord Protector of England, he vied for control of their nephew, the young King Edward VI ( r.

  6. John Michael Edward Seymour, 19th Duke of Somerset (b. 30 December 1952), married on 20 May 1978 Judith-Rose Hull, daughter of John Folliott Hull, and has issue: Sebastian Edward, Lord Seymour (b. 1982) Lady Sophia Rose Seymour (b. 1987) Lady Henriette Charlotte Seymour (b. 1989) Lord Charles Thomas George Seymour (b. 1992).

  7. Edward Seymour, 1st Duke of Somerset, Lord Protector of Edward VI (c. 1500 /1506 – 22 January 1552) married firstly Catherine, daughter of Sir William Fillol, and secondly Anne, daughter of Sir Edward Stanhope.