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  1. Sir Augustus Frederick d'Este, KCH (13 January 1794 – 28 December 1848) was a relative of the British royal family and the earliest recorded person for whom a definite diagnosis of multiple sclerosis can be made. He was the only son of Prince Augustus Frederick, Duke of Sussex and his wife Lady Augusta Murray.

  2. Sir Augustus Frederick DEsté (1794–1848) was an illegitimate royal child, a bachelor, an active member of the Aborigines Protection Society, and the earliest known person diagnosed with multiple sclerosis. For 24 years DEsté kept a diary, currently held in the Royal College of Physicians’ archives, which documents what he called ‘my case’.

  3. 17 de oct. de 2009 · Abstract. The personal diary of Sir Augustus dEsté, born 1794 grandson of King George III of England, reveals a medical history strongly suggesting that Augustus suffered from multiple sclerosis (MS). It could well be the first record of a person having this disease.

  4. La Casa d' Este. La Casa de Este es una dinastía principesca de origen franco que se dividió en dos ramas, la mayor es la conocida como Casa de Welf-Este o Casa de Welf; la menor es la Casa de Fulco-Este o más simplemente como la Casa de Este. Esta última originó una familia noble italiana, cuyos jefes fueron soberanos de Ferrara (1240 ...

  5. The personal diary of Sir Augustus d'Esté, born 1794 grandson of King George III of England, reveals a medical history strongly suggesting that Augustus suffered from multiple sclerosis (MS)....

  6. Abstract. The personal diary of Sir Augustus dEste ́, born 1794 grandson of King George III of England, reveals a medical history strongly suggesting that Augustus suffered from multiple...

  7. Finally, in December 1848, Augustus d'Este died at the age of 54 years, unmarried and without heirs, having suffered for 26 years from an initially intermittent disease with clinical relapses and remission of the symptoms, but with a gradual neurological deterioration. The disease had not, of course, been identified at that time.