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  1. Sir Augustus Frederick d'Este, KCH (13 January 1794 – 28 December 1848) was a relative of the British royal family and the earliest recorded person for whom a definite diagnosis of multiple sclerosis can be made. He was the only son of Prince Augustus Frederick, Duke of Sussex and his wife Lady Augusta Murray.

    • Augustus Frederick Hanover, 13 January 1794, London, Great Britain
    • 28 December 1848 (aged 54), Ramsgate, Kent
  2. Sir Augustus Frederick D’Esté (1794–1848) was an illegitimate royal child, a bachelor, an active member of the Aborigines Protection Society, and the earliest known person diagnosed with multiple sclerosis. For 24 years D’Esté kept a diary, currently held in the Royal College of Physicians’ archives, which documents what he called ‘my case’.

  3. 17 de oct. de 2009 · Abstract. The personal diary of Sir Augustus d’Esté, born 1794 grandson of King George III of England, reveals a medical history strongly suggesting that Augustus suffered from multiple sclerosis (MS). It could well be the first record of a person having this disease.

    • Anne Marie Landtblom, Patrik Fazio, Sten Fredrikson, Enrico Granieri
    • 2010
  4. The House of Este ( UK: / ˈɛsti / EST-ee, [7] US: / ˈɛsteɪ / EST-ay, [8] [9] Italian: [ˈɛste]) is a European dynasty of North Italian origin whose members ruled parts of Italy and Germany for many centuries. The original House of Este's elder branch, which is known as the House of Welf, included dukes of Bavaria and of Brunswick.

    • 1097; 926 years ago
  5. The personal diary of Sir Augustus d'Esté, born 1794 grandson of King George III of England, reveals a medical history strongly suggesting that Augustus suffered from multiple sclerosis (MS). It...

  6. The Case of Augustus d'Este (1794–1848): The First Account of Disseminated Sclerosis. D. Firth. Published in Proceedings of the Royal… 1 May 1941. Medicine. View on SAGE. ncbi.nlm.nih.gov. Save to Library. Create Alert. Cite. 25 Citations. Citation Type. More Filters. The first case history of multiple sclerosis: Augustus d’Esté (1794–1848)

  7. A young nobleman at the beginning of the nineteenth century. We owe the first documentation of multiple sclerosis (MS) to a descendent of the Estense family. Augustus d’Este ́ was born in 1794,...