Several dynastic marriages were considered for her from 1732 onward, including Frederick Lewis, Prince of Wales, Charles III of Spain and Louis of Hesse-Darmstadt, but none came to fruition. She was appointed co-adjutrix of Quedlinburg Abbey with the prospect of becoming a reigning princess-abbess in 1743, a future of which she did not approve.
hace 4 días · Louis IX, Landgrave of Hesse-Darmstadt: 5. Princess Frederica Louisa of Hesse-Darmstadt: 11. Countess Palatine Caroline of Zweibrücken: 1. Princess Charlotte of Prussia: 12. Duke Charles Louis Frederick of Mecklenburg-Strelitz: 6. Charles II, Grand Duke of Mecklenburg-Strelitz: 13. Princess Elisabeth Albertine of Saxe-Hildburghausen: 3.
On 10 November 1810 in Amalienborg Palace, she married Prince William of Hesse-Kassel. Her spouse was in Danish service from his youth, and the family lived in Denmark. The couple initially settled on Sankt Annæ Plads in central Copenhagen in what was called the Prince William Mansion.