John George was married twice. In addition to his successor John George II, he left three sons, Augustus (1614–1680), Christian (died 1691) and Maurice (died 1681). In Dresden on 16 September 1604 Johann Georg married firstly Sibylle Elisabeth, daughter of Frederick I, Duke of Württemberg. She died in the birth of their only child:
George I of Great Britain: 25. Sophia of the Palatinate: 6. George II of Great Britain: 26. George William, Duke of Brunswick-Lüneburg: 13. Sophia Dorothea of Celle: 27. Éléonore Desmier d'Olbreuse: 3. Anne, Princess Royal and Princess of Orange: 28. Albert II, Margrave of Brandenburg-Ansbach: 14. John Frederick, Margrave of Brandenburg ...
Frederick Charles, Duke of Württemberg-Winnental (father of 160) 321. Eleonore Juliane of Brandenburg-Ansbach (mother of 160) 322. Anselm Franz, 2nd Prince of Thurn and Taxis (father of 161) 323. Maria Ludovika Anna Franziska, Princess of Lobkowicz (mother of 161) 324. Philip William, Margrave of Brandenburg-Schwedt (father of 162) 325.
In April 1622, a large force belonging to Wilhelm, Duke of Saxe-Weimar and George Frederick, Margrave of Brandenburg-Ansbach assembled at the bridge to engage the imperial troops. Battle was joined at Wimpfen early in May and resulted in victory for the imperial forces.
After William's death, his wife became regent for their son George. Children that reached adulthood. Sophie of Brunswick-Lüneburg (30 October 1563 – 1639); married George Frederick, Margrave of Brandenburg-Ansbach. Ernest II, Duke of Brunswick-Lüneburg (31 December 1564 – 2 March 1611); Prince of Lüneburg from 1592–1611.
In 1792 it was occupied by Charles Alexander, Margrave of Brandenburg-Ansbach and his wife, and in 1820 by Caroline, consort of George IV. His non-political 'wife' was Maria Fitzherbert who lived in East End House in Parson's Green. They are reputed to have had several children.
Luther actually had grown a beard "sufficient to deceive his mother" and gone under the name "Junker George," which means "Knight George".  Shortly before Prince Frederick convinces Charles to give Luther a hearing at the Diet of Worms , the Emperor introduces Aleander to him as a "new cardinal", and Aleander's dress supports that.