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James, 1st Earl of Arran: Successor: James, 3rd Earl of Arran: Born: c. 1519: Died: 22 January 1575 Hamilton Castle, Lanarkshire, Scotland: Spouse(s) Margaret Douglas: Issue Detail: James, John, Claud, Anne & others: Father: James, 1st Earl of Arran: Mother: Janet Bethune
- c. 1519
- James, 1st Earl of Arran
- 1529–1575
- James, 3rd Earl of Arran
James, Claud, George, & others. Father. Claud Hamilton, 1st Lord Paisley. Mother. Margaret Seton. James Hamilton, 1st Earl of Abercorn PC (S) (1575–1618) was a Scottish diplomat for James VI and an undertaker (a term for an English colonist) in the Plantation of Ulster, Ireland.
John, 1st marquess of Hamilton (c. 1542-1604), third son of James Hamilton, 2nd earl of Arran (q.v.) and duke of Chatellerault, was given the abbey of Arbroath in 1551. In politics he was largely under the influence of his energetic and unscrupulous younger brother Claud, afterwards Baron Paisley (c. 1543
James and Margaret had nine children, five boys: James (1537–1609), succeeded him as the 3rd Earl of Arran but became insane in 1562; Gavin, died young; John (1540–1604), became the 1st Marquess of Hamilton; David (died 1611) Claud (1546–1621), from whom descend the earls, marquesses, and dukes of Abercorn —and four girls:
James (1537–1609), succeeded him as the 3rd Earl of Arran but became insane in 1562; Gavin, died young; John (1540–1604), became the 1st Marquess of Hamilton; David (died 1611) Claud (1546–1621), from whom descend the earls, marquesses and dukes of Abercorn —and four daughters: Barbara, married in 1553 James Fleming, 4th Lord Fleming
John and Claud were supporters of Mary Queen of Scots, and so in May 1579 the former Regent Morton seized Hamilton and Craignethan on the pretence of rescuing James from his imprisonment. John and Claud fled to England, but Arran, his mother, and Lord David were taken to Linlithgow, and his estates were taken over by the government.
10.1007/s00586-018-05873-3. The goal of this study was to refine clinical MRS to optimize performance and then determine whether MRS-derived biomarkers reliably identify painful discs, quantify degeneration severity, and forecast surgical outcomes for chronic low back pain (CLBP) patients.