Patrick Hepburn, 1st Earl of Bothwell (died 18 October 1508) was Lord High Admiral of Scotland. He rose to political prominence after supporting James IV against his father, and was proxy at the King's marriage.
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No Ataque de Chaseabout, Maria e suas forças e Stuart com os lordes revoltosos rodaram pela Escócia sem nunca entrarem em combate direito. Os números da rainha aumentaram com a libertação Jorge Gordon, 5.º Conde de Huntly, e o retorno da França de Jaime Hepburn, 4.º Conde de Bothwell.
Marriage to Margaret Tudor. In 1509, Douglas married Margaret Hepburn, daughter of the Earl of Bothwell.After her death, and that of his father, in 1513, on 6 August 1514 the new Earl of Angus married the dowager queen and regent, Margaret Tudor, widow of James IV, mother of two-year-old James V, and elder sister of Henry VIII of England.
Isabel I ou Elizabeth I (Greenwich, 7 de setembro de 1533 – Richmond, 24 de março de 1603), também chamada de "A Rainha Virgem", "Gloriana" ou "Boa Rainha Bess" ("Bess" era como Roberto Durdley, seu favorito, a chamava) foi Rainha da Inglaterra e Irlanda de 1558 até sua morte e a quinta e última monarca da Casa de Tudor.
July 31 – Pope Paul IV authorizes the creation of the University of Douai (which will later become the University of Lille).  August 15 – Led by Don Tristán de Luna y Arellano , a Spanish missionary colony of 1,500 men, on 13 ships, arrives from Vera Cruz at Pensacola Bay , founding the oldest European settlement in the mainland U.S. ( St. Augustine is founded in 1565 .)
The next Orkney title was the dukedom of Orkney, which was given to James Hepburn, 4th Earl of Bothwell, husband of Mary, Queen of Scots, in 1567. Later that year, however, he forfeited the title when Mary was forced to abdicate. Earls of Orkney, Second Creation. The second earldom was created by James VI of Scotland.