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  1. Christina of Lorraine or Christine de Lorraine (16 August 1565 – 19 December 1637) was a member of the House of Lorraine and was the Grand Duchess of Tuscany by marriage. She served as Regent of Tuscany jointly with her daughter-in-law during the minority of her grandson from 1621 to 1628.

  2. Soon after Grand Duchess Joanna had died, Francesco went on to marry his Venetian mistress, Bianca Cappello, after aptly disposing of her husband, a Florentine bureaucrat. Because of the quick remarriage and similar occurrences among the Medici (Francesco's younger brother Pietro had reportedly killed his wife), rumours spread that Francesco and Bianca had conspired to poison Joanna.