King Henry II, his father, arranged a remarkable betrothal for his son to Mary, Queen of Scots, in the Châtillon agreement of 27 January 1548, when Francis was only four years old. Mary had been crowned Queen of Scotland in Stirling Castle on 9 September 1543 at the age of nine months, following the death of her father James V .
Francis II, King of France: January 19, 1544: December 5, 1560: Married Mary, Queen of Scots (1542–1587) on 24 April 1558. They have no children. Elizabeth of France: April 2, 1545: October 3, 1568: Married Philip II, King of Spain (1527–1598) on 22 June 1559. They had six children but only two daughters survived. Claude of France