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NIOSH, CDC 2003. Tetrodotoxin is an extremely potent poison (toxin) found mainly in the liver and sex organs (gonads) of some fish, such as puffer fish, globefish, and toadfish (order Tetraodontiformes) and in some amphibian, octopus, and shellfish species.
3 de ene. de 2022 · Tetrodotoxin (TTX) is one of the most potent natural marine toxins, which acts by selectively blocking the action potentials of voltage-gated Na+ channels along nerves, skeletal and cardiac muscle membranes, without changing the resting membrane potentials.
Tetrodotoxin is produced by several species of the bacterium Vibronacea and it is the ingestion of these organisms that allows the toxin to accumulate within the fish. The toxin blocks voltage-gated sodium channels in excitable membranes of all tissues including brain, spinal cord, peripheral nerves, cardiac and skeletal muscle.
10 de oct. de 2016 · Tetrodotoxin (TTX) is a potent neurotoxin known from a wide array of taxonomic animal groups from almost all over the world. This toxin was first detected in puffer fishes of the family Tetraodontidae, which is where the name tetrodotoxin was derived from more than 100 years ago.
11 de mar. de 2019 · This review provides a comprehensive coverage of the history, biology and chemistry of tetrodotoxin (TTX). It traces the origin of this remarkable molecule all the way back to the ancient Chinese medicine records.
16 de dic. de 2019 · This review provides a comprehensive coverage of the history, biology and chemistry of tetrodotoxin (TTX). It traces the origin of this remarkable molecule all the way back to the ancient Chinese medicine records.
24 de jul. de 2021 · Tetrodotoxin (TTX) is a potent neurotoxin that was first identified in pufferfish but has since been isolated from an array of taxa that host TTX-producing bacteria. However, determining its origin, ecosystem roles, and biomedical applications has challenged researchers for decades.
