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27 de ago. de 2023 · ARREST is a prospective, parallel, multicentre, open-label, randomised superiority trial. Patients (aged ≥18 years) with return of spontaneous circulation following out-of-hospital cardiac arrest without ST elevation were randomly assigned (1:1) at the scene of their cardiac arrest by London Ambulance Service staff using a secure online randomisation system to expedited delivery to the ...
13 de nov. de 2020 · The ARREST trial, being a single centre trial, shows what it might be possible but does not definitively answer the question of whether this can be widely implemented. Reassuringly, the results of the ARREST trial accord with multiple cohorts. This suggests that the observed results might be replicated in other programmes.
3 de jul. de 2021 · Lancet.2020; 3961807-1816. Summary. The ARREST trial was a phase 2, single-centre, open-label, adaptive, safety and efficacy randomised clinical trial comparing early extracorporeal membrane oxygenation (ECMO)-facilitated resuscitation to standard advanced cardiac life support (ACLS) in adults with out-of-hospital refractory ventricular ...
5 de dic. de 2020 · The ARREST trial is registered with ClinicalTrials.gov, NCT03880565. Findings: Between Aug 8, 2019, and June 14, 2020, 36 patients were assessed for inclusion. After exclusion of six patients, 30 were randomly assigned to standard ACLS treatment (n=15) or to early ECMO-facilitated resuscitation (n=15).
25 de ene. de 2023 · In a trial conducted in the United States, Grunau et al. found a negative association between intraarrest transport and outcome in out-of-hospital cardiac arrest. 22 However, in a Dutch trial ...
14 de dic. de 2020 · Yannopoulos D, Bartos J, Raveendran G, Walser E, et al. Advanced reperfusion strategies for patients with out-of-hospital cardiac arrest and refractory ventricular fibrillation (ARREST): a phase 2, single centre, open-label, randomised controlled trial. Lancet. 2020 Nov 12:S0140-6736 (20)32338-2. doi: 10.1016/S0140-6736 (20)32338-2.
23 de ago. de 2023 · In adult patients without ST elevation, expedited transfer by ambulance to a cardiac arrest center following resuscitation from an out-of-hospital cardiac arrest (OHCA) did not reduce deaths compared with transfer to the closest emergency department, based on findings from the ARREST trial presented at ESC Congress 2023 and simultaneously published in The Lancet.
