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Charlotte Hellmich. Ms. NIHR Clinical Lecturer, Norwich Medical School. Email C.Hellmich @uea.ac .uk. MED. Overview. Network. Projects (3) Research output (17) Collaborations and top research areas from the last five years. Recent external collaboration on country/territory level. Dive into details by clicking on the dots or.
8 de dic. de 2021 · Acute infection is known to induce rapid expansion of hematopoietic stem cells (HSCs), but the mechanisms supporting this expansion remain incomplete. Using mouse models, we show that inducible CD36 is required for free fatty acid uptake by HSCs during acute infection, allowing the metabolic transition from glycolysis towards β ...
- 10.1038/s41467-021-27460-9
- 2021
- Nat Commun. 2021; 12: 7130.
28 de nov. de 2023 · Dominic Fowler-Shorten, Rebecca S Maynard, Katherine Hampton, Martha Ehikioya, Edyta E Wojtowicz, Kristian Bowles, Stuart Rushworth, Charlotte Hellmich; Acute Myeloid Leukemia Driven IL-3 Dependent Upregulation of BCL-2 in Non-Malignant Hematopoietic Progenitor Cells Increases Venetoclax Induced Cytopenias.
5 de nov. de 2020 · Jayna J Mistry, Charlotte Hellmich, Amelia Lambert, Jamie A Moore, Aisha Jibril, Angela Collins, Federica Di Palma, Kristian M Bowles, Stuart A Rushworth; Investigating the Dual Targeting of BCL-2 and CD38 in Models of Acute Myeloid Leukemia.
- Jayna J Mistry, Charlotte Hellmich, Amelia Lambert, Jamie A Moore, Aisha Jibril, Angela Collins, Fed...
- 2020
28 de nov. de 2023 · Charlotte Hellmich, Edyta E Wojtowicz, Dominic Fowler-Shorten, Rebecca S Maynard, Katherine Hampton, Iain Macaulay, Kristian Bowles, Stuart Rushworth; The Aging Bone Marrow Niche Disrupts Glutamine Metabolism By Upregulating HSC Derived Glutamine Synthetase.
13 de may. de 2021 · Jayna J Mistry 1 2 , Charlotte Hellmich 1 3 , Amelia Lambert 1 , Jamie A Moore 1 , Aisha Jibril 1 , Angela Collins 3 , Kristian M Bowles 4 5 6 , Stuart A Rushworth 7 8 Affiliations 1 Norwich Medical School, University of East Anglia, Norwich Research Park, NR4 7UQ, Norwich, UK.
OPEN. Freefatty-acidtransportviaCD36drives. β- oxidation-mediatedhematopoieticstemcell responsetoinfection. JaynaJ.Mistry1,2,5,CharlotteHellmich1,3,5,JamieA.Moore1,AishaJibril1,IainMacaulay2,...