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As a form of molecular medicine, targeted therapy blocks the growth of cancer cells by interfering with specific targeted molecules needed for carcinogenesis and tumor growth, rather than by simply interfering with all rapidly dividing cells (e.g. with traditional chemotherapy).
- Targeted therapy of lung cancer
Targeted therapy of lung cancer refers to using agents...
- Targeted therapy of lung cancer
- How Is Targeted Therapy given?
- Where Do I Go For Targeted Therapy?
- How Often Will I Receive Targeted Therapy?
- How Will Targeted Therapy Affect Me?
- How Will I Know Whether Targeted Therapy Is working?
Small-molecule drugs are pills or capsules that you can swallow. Monoclonal antibodies are usually given through a needle in a blood vein.
Where you go for treatment depends on which drugs you are getting and how they are given. You may take targeted therapy at home. Or you may receive targeted therapy in a doctor’s office, clinic, or outpatient unit in a hospital. Outpatient means you do not spend the night in the hospital.
How often and how long you receive targeted therapy depends on 1. your type of cancer and how advanced it is 2. the type of targeted therapy 3. how your body reacts to treatment You may have treatment every day, every week, or every month. Some targeted therapies are given in cycles. A cycle is a period of treatment followed by a period of rest. Th...
Targeted therapy affects people in different ways. How you feel depends on how healthy you are before treatment, your type of cancer, how advanced it is, the kind of targeted therapy you are getting, and the dose. Doctors and nurses cannot know for certain how you will feel during treatment.
While you are receiving targeted therapy, you will see your doctor often. He or she will give you physical exams and ask you how you feel. You will have medical tests, such as blood tests, x-rays, and different types of scans. These regular visits and tests will help the doctor know whether the treatment is working.
The 2 most common types of targeted therapy are monoclonal antibodies and small-molecule inhibitors. Monoclonal antibodies target specific proteins, often receptors, on the cancer cell’s surface 6 or in the environment around the tumour. These large molecules are not able to enter the cell.
- Sian L. Shuel
- Can Fam Physician. 2022 Jul; 68(7): 515-518.
- 10.46747/cfp.6807515
- 2022/07
Targeted therapy is a type of cancer treatment. It uses drugs to target specific genes and proteins that help cancer cells survive and grow. Targeted therapy can affect the tissue environment that cancer cells grow in or it can target cells related to cancer growth, like blood vessel cells. Targeted therapy can treat many different types of cancer.
Targeted therapies work by influencing the processes that control growth, division, and spread of cancer cells, as well as the signals that cause cancer cells to die naturally. Learn about the history targeted therapy here.
The effectiveness of targeted α-therapy (TAT) can be explained by the properties of α-particles. Alpha particles are helium nuclei and are ~8,000 times larger than β − -particles (electrons). When emitted from radionuclides that decay via an α-decay pathway, they release enormous amounts of energy over a very short distance.
