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  1. Hace 1 día · Classic explanations include yellow fever, bubonic plague, influenza, smallpox, chickenpox, typhus, and syndemic infection of hepatitis B and hepatitis D. 1,143,000–3,429,000 (estimated 30–90% of population) [68] [69] 1629–1631 Italian plague (part of the second plague pandemic ) 1629–1631. Italy. Bubonic plague.