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Guanfacine, sold under the brand name Tenex (immediate-release) and Intuniv (extended-release) among others, is an oral alpha-2a agonist medication used to treat attention deficit hyperactivity disorder (ADHD) and high blood pressure. [2] [7] Guanfacine is FDA-approved for monotherapy treatment of ADHD, [2] as well as being used for ...
chemical compound
16 de abr. de 2021 · Guanfacine is a selective agonist of the α2A adrenoceptor [11,12,13,14]. The α2A adrenoceptor is mainly expressed in the dendritic spines of frontal glutamatergic pyramidal neurones . Based on the findings, the major mechanisms of action of guanfacine are proposed as two hypotheses [7,14,15].
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Generic Name Guanfacine DrugBank Accession Number DB01018 Background. Guanfacine, or BS 100-141, 8,9 is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension 10 but is now indicated as an extended release tablet for the treatment of ADHD. 11 Guanfacine was first described in the literature in 1974. 9
Vance Drummond (1927–1967) was a New Zealand–born Australian pilot who fought in the Korean and Vietnam Wars. Posted to No. 77 Squadron in Korea, he flew Gloster Meteor jet fighters and earned the US Air Medal for his combat skills. He was shot down in 1951 and imprisoned for almost two years. He was awarded the Air Force Cross in 1965 ...
Guanosine ( symbol G or Guo) is a purine nucleoside comprising guanine attached to a ribose ( ribofuranose) ring via a β-N 9 - glycosidic bond. Guanosine can be phosphorylated to become guanosine monophosphate (GMP), cyclic guanosine monophosphate (cGMP), guanosine diphosphate (GDP), and guanosine triphosphate (GTP).
