His son Evelyn Cecil was a Conservative politician and was created Baron Rockley in 1934. The Right Reverend Lord William Gascoyne-Cecil, Bishop of Exeter, Robert Cecil, 1st Viscount Cecil of Chelwood, Lord Edward Cecil and Hugh Cecil, 1st Baron Quickswood, were all younger sons of the third Marquess.
Hon. Fanny Georgina Mildred Cecil (1865 – 24 April 1867) Lord Edward Herbert Cecil (12 July 1867 – 13 December 1918); he married Violet Maxse on 18 June 1894. They had two children. Lord Hugh Richard Heathcote Cecil, 1st Baron Quickswood (14 October 1869 – 10 December 1956)
Gascoyne-Cecil, Hugh Richard Heathcote, (1869-1956), Baron Quickswood, politician Gascoyne-Cecil, James Edward Hubert, (1861-1947), 4th Marquess of Salisbury Gascoyne-Cecil, Robert Arthur Talbot, (1830-1903), 3rd Marquess of Salisbury, statesman