Her mother was Caroline of Ansbach, daughter of Johann Friedrich, Margrave of Brandenburg-Ansbach. As a granddaughter of the Elector of Hanover, she was styled Princess Caroline of Hanover at birth. Under the Act of Settlement 1701, she was seventh in the line of succession to the British throne.
In 1603, Hohenzollern Elector Joachim III Frederick of Brandenburg separately inherited the Silesian Duchy of Jägerndorf from his cousin, Margrave George Frederick of Brandenburg-Ansbach, and installed his second son, Johann Georg, as duke.
In Altenburg on 24 October 1636, Ernst married his cousin Elisabeth Sophie of Saxe-Altenburg. As a result of this marriage Saxe-Gotha and Saxe-Altenburg were unified, when the last duke of the line (Elisabeth's cousin) died childless in 1672. Ernst and Elisabeth Sophie had eighteen children: Johann Ernest (b. Weimar, 18 September 1638 – d.
Christian Heinrich, Margrave of Brandenburg-Kulmbach: 5. Sophie Magdalene of Brandenburg-Kulmbach: 11. Sophie Christiane of Wolfstein: 1. Christian VII of Denmark: 12. George I of Great Britain: 6. George II of Great Britain: 13. Sophia Dorothea of Celle: 3. Louise of Great Britain: 14. John Frederick, Margrave of Brandenburg-Ansbach: 7 ...
Ernst IV. († 1496) Erich von Braunschweig-Grubenhagen (1478–1532), Bischof von Osnabrück, Paderborn und Münster; Sophie, Äbtissin von Gandersheim; Johann II. († wohl 1401) Ernst von Braunschweig-Grubenhagen (Abt) († 1400/1402), 1369–1371 Abt von Corvey, 1372–1402 Propst am Alexanderstift in Einbeck
She was the firstborn child of Christian Ernst, Margrave of Brandenburg-Bayreuth, and his second wife, Princess Sophie Luise of Württemberg, daughter of Eberhard III, Duke of Württemberg. She was named for her father, Christian, and her mother's father, Eberhard. As the daughter of the Margrave of Brandenburg-Bayreuth, she was margravine by
Leonhart Fuchs (German: [ˈleːɔnhaʁt ˈfʊks]; 17 January 1501 – 10 May 1566), sometimes spelled Leonhard Fuchs and cited in Latin as Leonhartus Fuchsius, was a German physician and botanist.